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(S)-3-Hydroxy-gamma-butyrolactone

 

Identification
Molecular Structure CAS No. 7331-52-4
Molecular Formula C4H6O3
Molecular Weight 102.09
Name (S)-3-Hydroxy-gamma-butyrolactone
Synonymous
Properties
Boiling Point 98-100°C (0.3 mmHg)
Density 1.24
Flash Point >110°C
Safety & Transportation Information
Harzard Symbols
Hs code
Supplier Specification
Appearance Colorless liquid
Purity 99%+
Packages 25kg, 200kg/drum
Productivity MTs
Storage Kept airtightly in a light-proof, dry and cool place
Notes  important intermediate in organic  synthesis and an important chiral pool.It is mainly used in the synthesis of some natural products and some bioactive chiral drugs or antibiotic chiral drugs.For example,it is a key intermediate in  synthesis of.nerve regulator (R)-GABOB and brain metabolic accelerant (S)-Oxiracetam. s-3-Hydroxy-γ-butyrolactone cart be deoxidized to (S)-3-hydroxy-tetrahydrofurane which is an important intermediate of anti-AIDS drugs.It is also used in the synthesis of (S)-3-hydroxy-4-bromobutyric acid which is a potential stabilizer.It can also be used to produce (S)-5-hydroxymethyl-oxazolin which is a new antibiotic drug.
Besides, both(S)-N-methyl-hydroxypyrrole and(R)-N-methyl-3-methylamino-pyrrole have important bioactivity, and they can be made from s-3-Hydfoxy-γ-butyrolactone by simple reaction.Furthermore,s-3-Hydroxy-Y-butyrolactone can Synthesize many natural products.
 
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