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| Identification |
| Molecular Structure |
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CAS No. |
7331-52-4 |
| Molecular Formula |
C4H6O3 |
| Molecular Weight |
102.09 |
| Name |
(S)-3-Hydroxy-gamma-butyrolactone |
| Synonymous |
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| Properties |
| Boiling Point |
98-100°C (0.3 mmHg)
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| Density |
1.24
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| Flash Point |
>110°C
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| Safety & Transportation Information |
| Harzard Symbols |
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| Hs code |
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| Supplier Specification |
| Appearance |
Colorless liquid
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| Purity |
99%+
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| Packages |
25kg, 200kg/drum
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| Productivity |
MTs
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| Storage |
Kept airtightly in a light-proof, dry and cool place
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| Notes |
important intermediate in organic synthesis and an important chiral pool.It is mainly used in the synthesis of some natural products and some bioactive chiral drugs or antibiotic chiral drugs.For example,it is a key intermediate in synthesis of.nerve regulator (R)-GABOB and brain metabolic accelerant (S)-Oxiracetam. s-3-Hydroxy-γ-butyrolactone cart be deoxidized to (S)-3-hydroxy-tetrahydrofurane which is an important intermediate of anti-AIDS drugs.It is also used in the synthesis of (S)-3-hydroxy-4-bromobutyric acid which is a potential stabilizer.It can also be used to produce (S)-5-hydroxymethyl-oxazolin which is a new antibiotic drug.
Besides, both(S)-N-methyl-hydroxypyrrole and(R)-N-methyl-3-methylamino-pyrrole have important bioactivity, and they can be made from s-3-Hydfoxy-γ-butyrolactone by simple reaction.Furthermore,s-3-Hydroxy-Y-butyrolactone can Synthesize many natural products.
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