Hindered sulphonyl chlorides have found use as condensing agents for the formation of the phosphate link of oligonucleotides [1,2,3]; of oligonucleotide synthesis by the phosphotriester method [4,5]; use as a condensing agent in the synthesis of H-phosphonate diesters[6].  More hindered in comparison with, e.g. Mesitylenesulfonyl chloride, and so has less tendency to react with the free 5'-hydroxyl group of sugares[7].

Ref:

1. Angew.  Chem. Int. Ed., 11, 451(1972)
2. Synthesis,  222(1975)
3. Chem. Rev.,  77, 183(1977)
4. Heterocycles, 7, 1197(1977)
5. Tetrahedron, 34, 3443(1978)
6. Nucleosides Nucleotides, 7, 23(1988)
7. J. Am. Chem. Soc.,  88, 829(1966)