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Silibinin

 

Identification
Molecular Structure CAS No. 22888-70-6
Molecular Formula C25H22O10
Molecular Weight 482.44
Name Silibinin
Synonymous Silybinin; Silliver; Silybine;Silibinin; (2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-7-yl]chroman-4-one
Properties
Melting Point Not available
Safety & Transportation Information
Harzard Symbols
Hs code
Supplier Specification
Appearance crystalline solid
Purity 98%
Packages
Productivity
Storage
Notes Silybin (silibinin) is the major flavonolignan from the extracts of milk thistle seed, Silybum marianum. The whole extract, known as silymarin, has been found to protect the liver from both acute and chronic toxicity and injury. Silybin  is used in the treatment and prevention of liver diseases because of its hepatoprotective (antihepatotoxic) properties. Clinical tests have also shown its ability to protect against certain types of cancer (skin and prostate), probably due to its antioxidant properties.

Chemically modified silibinin, silibinin dihydrogen disuccinate disodium  a solution for injection, is used in treatment of severe intoxications with hepatotoxic substances, such as death cap (Amanita phalloides) poisoning.
 
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