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O-(Benzotriazol-1-yl)-N,N,N',N'-bis(pentamethylene)uronium hexafluorophosphate

 

Identification
Molecular Structure CAS No. 206752-41-2
Molecular Formula C17H24F6N5OP
Molecular Weight 459.37
Name O-(Benzotriazol-1-yl)-N,N,N',N'-bis(pentamethylene)uronium hexafluorophosphate
Synonymous HBPipU
Properties
Melting Point 206 °C (dec.)
Safety & Transportation Information
Harzard Symbols
Hs code
Supplier Specification
Appearance White powder
Purity 98%+
Packages On request.
Productivity Kgs.
Storage Keep cool and dry.
Notes
Recent studies show that crystal and solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound1 ; Non-hygroscopic, extremely reactive reagent for peptide coupling. It is an analogue of the bis(tetramethylene) derivative described recently2
  • P. Henklein et al. Proc. 24th Eur. Pept. Symp.: Peptides 1996 Kingswinford , UK , 465, (1998)
  • S. Chen, J. Xu Tet. Lett. 33 , 647, (1992)
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